Put together by collector Mark Ottignon, it is one of the most extensive consignments of Beatrix Potter related material to come up for auction since the 1997 Doris Frohnsdorff sale at Christie's.
Many lots are highly scarce but, due to the wide variety of items, it also offers something for enthusiasts on a lower budget as well.
The rarities include A Happy Pair from 1890, the first book illustrated throughout by Beatrix Potter herself. The six chromolithographed illustrations of anthropomorphised rabbits in the book were based on her own pet, Bouncer, and were originally used as card designs that she had sent to Hildesheimer & Faulkner for which she was paid £6 - incidentally the start of her professional career.
The images were published in this small booklet with the addition of verses by the Victorian songwriter Frederick Weatherly.
The estimate is £12,000-16,000.
Further highlights can be viewed via the image slideshow on this page.
The sale will take place at Bloomsbury Auction's Maddox Street saleroom on February 27 at 2pm.
Tel: 020 7495 9494.